pTDT

Polygenic transmission disequilibrium test in case-parent trios for direct PGS effect

Usage

ptdt(pgs_c, pgs_m, pgs_f, side0 = 2)

Arguments

pgs_c

The PGS values of the affected probands (children). A vector of length N, no missing values are allowed

pgs_m

The PGS values of mothers that corresponds to the children. A vector of same length N, no missing values are allowed

pgs_f

The PGS values of fathers that corresponds to the children. A vector of same length N, no missing values are allowed

side0=2

Sided of the t test, default is 2-sided.

Value

Results of pTDT

statistic

Results of polygenic transmission disequilibrium test